Bone Tissue Engineering

Bone Tissue Engineering in the field of Regenerative Medicine has been the topic of substantial research over the past two decades. Technological advances have improved orthopaedic implants and surgical techniques for bone reconstruction. Bone tissue engineering is concerned with creating implantable bone substitutes for critical skeletal defects that cannot heal on their own. These defects are common clinical scenarios in orthopedics and craniofacial surgery, for the treatment of bone loss due to trauma, infection, and tumor resection. In the conventional tissue-engineering paradigm, combinations of cells and bioactive molecules are seeded onto three-dimensional biomaterial scaffolds to create an implantable ‘osteogenic’ implant.

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